منابع مشابه
Reducing Relapse in Psychosis through Medication Management
MHP161 2 Reducing relapse in psychosis through medication management.
متن کاملOrexin Receptor Targets for Anti-Relapse Medication Development in Drug Addiction
Drug addiction is a chronic illness characterized by high rates of relapse. Relapse to drug use can be triggered by re-exposure to drug-associated cues, stressful events, or the drug itself after a period of abstinence. Pharmacological intervention to reduce the impact of relapse-instigating factors offers a promising target for addiction treatment. Growing evidence has implicated an important ...
متن کاملSimple synthesis of modafinil derivatives and their anti-inflammatory activity.
Simple synthesis of modafinil derivatives and their biological activity are described. The key synthetic strategies involve substitution and coupling reactions. We determined the anti-inflammatory effects of modafinil derivatives in cultured BV2 cells by measuring the inhibition of nitrite production and expression of iNOS and COX-2 after LPS stimulation. It was found that for sulfide analogues...
متن کاملR-modafinil (armodafinil): a unique dopamine uptake inhibitor and potential medication for psychostimulant abuse.
BACKGROUND (±)-Modafinil has piqued interest as a treatment for attention-deficit/hyperactivity disorder and stimulant dependence. The R-enantiomer of modafinil might have unique pharmacological properties that should be further investigated. METHODS (±)-Modafinil and its R-(-)- and S-(+)-enantiomers were synthesized and tested for inhibition of [(3)H] dopamine (DA) uptake and [(3)H]WIN 35428...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Neuropsychopharmacology
سال: 2009
ISSN: 0893-133X,1740-634X
DOI: 10.1038/npp.2009.123